Imaging core

Overall aim

This research line focuses on structural imaging markers for neurodegenerative disorders and cancer. An important part is neuroimaging, but also with work on whole-body MRI. High-dimensional imaging markers, consisting of millions of variable describing organ structure, are an important part of this. This research line focuses on structural imaging markers for neurodegenerative disorders and cancer. An important part is neuroimaging, but also with work on whole-body MRI. High-dimensional imaging markers, consisting of millions of variable describing organ structure, are an important part of this.

Neuroimaging, i.e. cranial MRI, CT
Whole-body MRI
Cellular imaging

Active team members

Hieab Adams

Principal investigator

Tavia Evans

Postdoctoral researcher

Maria Knol

PhD candidate

Sander Lamballais

Postdoctoral researcher

Partha Haldar

Researcher

Natalia Vilor-Tejedor

Postdoctoral researcher

News

Subcortical GWAS published in Nature Genetics

Subcortical GWAS published in Nature Genetics

QDECR software at Human Brain Mapping conference in Rome

QDECR software at Human Brain Mapping conference in Rome

Telorism data processed for 35.000 scans

Telorism data processed for 35.000 scans

Journal club on machine learning in clinical prediction

Journal club on machine learning in clinical prediction

JPND working group statement published

JPND working group statement published

Acceptance abstracts to ESHG 2019

Acceptance abstracts to ESHG 2019

New R package launched by SandeR Lamballais

New R package launched by SandeR Lamballais

Partha Haldar submits grant for UNITED consortium extension in India

Partha Haldar submits grant for UNITED consortium extension in India

Literature of all published imaging studies in neurodegeneration research

Literature of all published imaging studies in neurodegeneration research

Paper on cognition genes published in Aging

Paper on cognition genes published in Aging

Projects

Strategies for integrated analysis in Neurogenetic / Imaging Genetics studies

Strategies for integrated analysis in Neurogenetic / Imaging Genetics studies

Uncovering the genetic characterization of hippocampal subfields

Uncovering the genetic characterization of hippocampal subfields

Evaluating brain atrophy as an endophenotype for genetic studies of neurodegeneration

Evaluating brain atrophy as an endophenotype for genetic studies of neurodegeneration

Migraine genetic variants and their influence on cerebral blood flow

Migraine genetic variants and their influence on cerebral blood flow

Genetic correction of hippocampal volume in dementia prediction

Genetic correction of hippocampal volume in dementia prediction

Gene expression and its effects on the cerebral cortex

Gene expression and its effects on the cerebral cortex

Genetic factors predisposing to brain microbleeds

Genetic factors predisposing to brain microbleeds

Genome-wide association study of human head size

Genome-wide association study of human head size

Genetics of cognition and markers of neurodevelopment and neurodegeneration

Genetics of cognition and markers of neurodevelopment and neurodegeneration

Orbital telorism and neural correlates

Orbital telorism and neural correlates

Heritability and genome-wide association studies of orbital telorism

Heritability and genome-wide association studies of orbital telorism

Does polygenic burden for late-life neurodegeneration relate to early-life processes?

Does polygenic burden for late-life neurodegeneration relate to early-life processes?

Genetic scores for region-specific subcortical volume during adulthood generalize to infancy and early childhood

Genetic scores for region-specific subcortical volume during adulthood generalize to infancy and early childhood

qdecR: an R package for surface-wide analyses of FreeSurfer segmentations

qdecR: an R package for surface-wide analyses of FreeSurfer segmentations

High-dimensional imaging markers and neurodegenerative disorders: a pilot study

High-dimensional imaging markers and neurodegenerative disorders: a pilot study

Genetic architecture of subcortical brain structures

Genetic architecture of subcortical brain structures

Planar cell polarity pathway and development of the human visual cortex

Planar cell polarity pathway and development of the human visual cortex

Literature review of imaging research of neurodegeneration