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Maria Knol

Drs. Maria Knol


After I obtained my BSc in Medicine I followed a research master in Clinical Epidemiology. I performed my master and PhD research at the department of Epidemiology of the Erasmus MC University Medical Center. Currently, I am following the master in Medicine and finalizing my PhD thesis.

The main focus of my research is on omics data within the field of complex neurological diseases. On one hand, I am working on new omics discoveries, mainly using brain imaging markers. On the other hand, I am using omics discoveries in order to understand the underlying pathophysiology of neurological diseases and related traits. Ultimately, my goal is to translate these omics discoveries to the clinic, e.g. by including them in disease prediction tools.

  • PhD researcher, department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands
  • Damotte, V., van der Lee, S. J., Chouraki, V., Grenier-Boley, B., Simino, J., Adams, H., Tosto, G., White, C., Terzikhan, N., Cruchaga, C., Knol, M. J., Li, S., Schraen, S., Grove, M. L., Satizabal, C., Amin, N., Berr, C., Younkin, S., Alzheimer’s Disease Neuroimaging Initiative, Gottesman, R. F., … van Duijn, C. M. (2021). Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants. Alzheimer’s & dementia : the journal of the Alzheimer’s Association, 10.1002/alz.12333. Advance online publication.
  • Li, S., Weinstein, G., Zare, H., Teumer, A., Völker, U., Friedrich, N., Knol, M. J., Satizabal, C. L., Petyuk, V. A., Adams, H., Launer, L. J., Bennett, D. A., De Jager, P. L., Grabe, H. J., Ikram, M. A., Gudnason, V., Yang, Q., & Seshadri, S. (2020). The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages. Brain communications2(2), fcaa176.
  • Sargurupremraj, M., Suzuki, H., Jian, X., Sarnowski, C., Evans, T. E., Bis, J. C., Eiriksdottir, G., Sakaue, S., Terzikhan, N., Habes, M., Zhao, W., Armstrong, N. J., Hofer, E., Yanek, L. R., …, Knol, M.J.,… Hagenaars, S. P., Kumar, R. B., van den Akker, E. B., McWhirter, R. E., Trompet, S., Mishra, A., … Debette, S. (2020). Cerebral small vessel disease genomics and its implications across the lifespan. Nature communications11(1), 6285.
  • Hofer, E., Roshchupkin, G. V., Adams, H., Knol, M. J., Lin, H., Li, S., Zare, H., Ahmad, S., Armstrong, N. J., Satizabal, C. L., Bernard, M., Bis, J. C., Gillespie, N. A., Luciano, M., Mishra, A., Scholz, M., Teumer, A., Xia, R., Jian, X., Mosley, T. H., … Seshadri, S. (2020). Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. Nature communications11(1), 4796.
  • Knol, M. J., Lu, D., Traylor, M., Adams, H., Romero, J., Smith, A. V., Fornage, M., Hofer, E., Liu, J., Hostettler, I. C., Luciano, M., Trompet, S., Giese, A. K., Hilal, S., van den Akker, E. B., Vojinovic, D., Li, S., Sigurdsson, S., van der Lee, S. J., Jack, C. R., Jr, … Alzheimer’s Disease Neuroimaging Initiative (2020). Association of common genetic variants with brain microbleeds: A genome-wide association study. Neurology95(24), e3331–e3343.

Click here for all her publications.